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Medical Entrance Exam
OTI365 - Medical Jipmer
JIMPER Biology - Human Health and Disease Important Questions

Biology - Human Health and Disease

Exam Duration: 45 Mins Total Questions : 30

1 )

A disease which often produces deformities of fingers and toes is

(a)
Poliomyelitis
(b)
Filariasis
(c)
Malaria
(d)
Leprosy

2 )

In which one of the following diseases, fever must not be managed using Aspirin, instead paracetamol should be used?

(a)
Typhoid
(b)
Filariasis
(c)
Pneumonia
(d)
Dengue fever

3 )

The top two tips of Y-shaped antibody molecule bind to the specific antigen in a lock and key fashion, this binding is not facilitated by

(a)
Covalent bonding
(b)
Electrostatic bonds
(c)
Hydrogen bonding
(d)
ionic bonds

4 )

Events in body defence against infection occur in the following sequence.

(a)
Inflammation, chemotaxis, diapedesis and phagocytosis
(b)
Inflammation, dipedesis, chemotaxis and phagocytosis
(c)
Diapedesis, phagocytosis, chemotaxis and inflammation
(d)
Diapedesis, chemotaxis, phagocytosis and inflammation

5 )

Vaccines produced through genetic engineering are safe as

(a)
they are least active forms of virus
(b)
they show attenuated forms of pathogen
(c)
they contain antigen only from the coat of pathogen
(d)
All of these

6 )

Diphteria antitoxin must be given within 24 hours of first appearance of the symptoms of diphtheria. Antitoxin contains

(a)
antibiotic
(b)
antibody
(c)
antigen
(d)
toxoid

7 )

Select the correct statement from the ones given below?

(a)
Barbiturates when given to criminals make them tell the truth
(b)
Morphine is often given to persons who have undergone surgery as a pain kliller
(c)
Chewing tobacco lowers blood pressure and heart rate
(d)
Cocaine is given to patients after surgery as it stimulates recovery

8 )

Where will you look for the sporozoites of the malarial parasite?

(a)
Saliva of infected female Anopheles mosquito
(b)
Salivary glands of freshly moulted female Anopheles mosquito
(c)
Spleen of infected humans
(d)
RBCs of humans suffering from malaria

9 )

At which stage of HIV infection does one usually show symptoms of AIDS?

(a)
When the infecting retrovirus enters host cells
(b)
When viral DNA is produced by reverse transcriptase
(c)
When HIV replicates rapidly in helper T-lymphocytes and damages large number of these
(d)
Within 15 days of sexual contact with an infected person

10 )

Which one of the following statements is correct with respect to immunity?

(a)
Preformed antibodies need to be injected to treat the bite of a viper snake
(b)
The antibodies against small pox pathogen are produced by t-lymphocytes
(c)
Antibodies are protein molecules, each of which has four light chains
(d)
Rejection of a kidney graft is the function of B-Iymphocytes

11 )

The genes which upon activation produce malignant neoplasms are called

(a)
pleiotropic genes
(b)
multiple genes
(c)
proto-oncogenes
(d)
neonatal genes

12 )

Human immunodeficiency virus is a/an

(a)
Adeno virus
(b)
DNA retrovirus
(c)
RNA retrovirus
(d)
Adeno retrovirus

13 )

Which of the following is correctly matched?

(a)
Thyroxine - Tetanus
(b)
Insulin - Diabetes insipidus
(c)
Adrenaline - hepatitis
(d)
parathyroid - Tetany

14 )

Which of the following pairs contains an infectious and a non-infectious disease respectively?

(a)
Typhoid and AIDS
(b)
AIDS and cancer
(c)
Pneumonia and malaria
(d)
Cancer and malaria

15 )

Which of the following diseases is transmitted by the bite of the female mosquito vector?

(a)
Filariasis
(b)
Amoebiasis
(c)
Typhoid
(d)
Pneumonia

16 )

Read the following statements and select the correct option.
Statement 1: The exaggerated response of the immune system to certain antigens present in the environment is called as allergy.
Statement 2: The allergic tendency is genetically passed from the parent to the offspring and is characterised by the presence of large quantities of IgG antibodies in the blood.

(a)
Both statements 1 and 2 are correct
(b)
Statement 1 is correct but statement 2 is incorrect
(c)
Statement 1 is incorrect but statement 2 is correct
(d)
Both statements 1 and 2 are incorrect

17 )

Read the following statements and select the correct option.
Statement 1: When the immune system fails to recognise 'self' from 'nonself and starts destroying body's own proteins, this leads to auto-immune diseases. Statement 2: Addison's disease and rheumatoid arthritis are auto-immune diseases.

(a)
Both statements 1 and 2 are correct.
(b)
Statement 1 is correct but statement 2 is incorrect
(c)
Statement 1 is incorrect but statement 2 is correct
(d)
Both statements 1 and 2 are incorrect

18 )

The primary lymphoid organs are

(a)
spleen and thymus
(b)
bone marrow and thymus
(c)
bone marrow and lymph node
(d)
thymus and MALT

19 )

Charas and ganja are the drugs which affect

(a)
respiratory system
(b)
cardiovascular system
(c)
digestive system
(d)
nervous system

20 )

________ is a CNS stimulant as it interferes with the transport of the neuro-transmitter _________

(a)
Cocaine, acetylcoline
(b)
Barbiturate, glutamate
(c)
Cocaine, dopamine
(d)
Barbiturate, glycine

21 )

The addictive chemical present in tobacco is

(a)
caffeine
(b)
nicotine
(c)
catechol
(d)
carbon monoxide

22 )

Transplantation of tissues/organs to save certain patients often fails due to rejection of such tissues/organs by the patient. Which type of immune response is responsible for such rejections?

(a)
Auto-immune response
(b)
Humoral immune response
(c)
Physiological immune response
(d)
Cell-mediated immune response

23 )

Assertion : Virus-infected cells secrete proteins known as interferons.
Reason : Interferons protect the non-infected cells from bacterial infection.

(a)
If both assertion and reason are true and reason is the correct explanation of assertion.
(b)
If both assertion and reason are true but reason is not the correct explanation of assertion.
(c)
If assertion is true but reason is false.
(d)
If both assertion and reason are false.

24 )

Assertion : Opioids help to enhance respiratory activity.
Reason : Opioids are the drugs which binds to specific opioid receptors present in respiratory tract.

(a)
If both assertion and reason are true and reason is the correct explanation of assertion.
(b)
If both assertion and reason are true but reason is not the correct explanation of assertion.
(c)
If assertion is true but reason is false.
(d)
If assertion is true but reason is false.

25 )

The cells that actually release the antibodies are

(a)
Helper T-cells
(b)
Cytotoxic T-cells
(c)
Plasma cells
(d)
Memory cells

26 )

Typhoid fever could be confirmed by

(a)
Widal test
(b)
Mantoux test
(c)
Schick test
(d)
Dick test

27 )

Wuchereria bancroftl, the filarial worm that causes elephantiasis belongs to phylum

(a)
Platyhelminthes
(b)
Aschelminthes
(c)
Coelenterate
(d)
Arthropoda

28 )

Oncogene is another name for

(a)
Inducer gene
(b)
Jumping gene
(c)
Structural gene
(d)
Cancer causing gene

29 )

Ringworm in humans is caused by

(a)
Viruses
(b)
Bacteria
(c)
Fungi
(d)
Nematodes

30 )

What is true about T lymphocytes in mammals?

(a)
There are three main types - cytotoxic T cells, helper T cells and suppressor T cells
(b)
These originate in secondary lymphoid tissues
(c)
They scavenge damaged cells and cellular debris
(d)
These are produced in thyroid