Biology - Genetics
Exam Duration: 60 Mins Total Questions : 30
Who proposed 3-D helical DNA model?
- (a)
Franklin and Wilkins
- (b)
Watson and Crick
- (c)
Yanofsky
- (d)
Meselson and Stahl
Haemophilia is a genetic disorder which lead to
- (a)
the decrease in hemoglobin level
- (b)
rheumatic heart disease
- (c)
The decrease in WBC
- (d)
non-clotting of blood
Mendel worked on
- (a)
edible pea
- (b)
wild pea
- (c)
garden pea
- (d)
pigeon pea
What is the most conspicuous salient feature of people with 'progeria'?
- (a)
More hair on body
- (b)
Less immunity to opportunistic infections
- (c)
Faster rate of ageing
- (d)
Suffer from infertility.
The phenomena in which one gene controls two or more different characters simultaneously? is called
- (a)
apomixis
- (b)
oleiotropy
- (c)
polyploidy
- (d)
polyteny
Down's syndrome is due to
- (a)
chromosome number increase in 21st pair autosome.
- (b)
chromosome number decreases in 21st pair autosome.
- (c)
chromosome number increase in 18th pair autosome.
- (d)
chromosome number decreases in 18th pair autosome.
Who is the responsible for the sex determination of a child?
- (a)
Father
- (b)
Mother
- (c)
Both a and b
- (d)
None of these
The nucleosome is
- (a)
histone proteins
- (b)
DNA wrapped around histones
- (c)
RNA wrapped around Histones
- (d)
DNA wrapped around acidic protein
In prokaryotes, multiple ribosomes (polysomes) participate in
- (a)
translation process
- (b)
transcription process
- (c)
linkage
- (d)
crossing over
Jumping genes/transposons / movable genetic elements discovered by Barbara McClintock in
- (a)
Maize
- (b)
Wheat
- (c)
Barely
- (d)
rice
Consider the following statements:
1. The genetic code is a sequence of nucleotide bases in mRNA encoding the information for protein synthesis; determines the sequence of amino acids in proteins .
2. The genetic code is a triplet.
3. Holley, Nirenberg, and Khurana got Nobel Prize for decoding genetic information.
Which of the statements given above are correct about genetic code?
- (a)
Only 1
- (b)
Only 2
- (c)
1 and 2
- (d)
1,2 and 3
Match List I(Antibiotics) with List II(Effect) and select the correct answer using the codes given below the lists:
List I | List II |
A. Neomycin | 1. Inhibits interaction between mRNA and tRNA |
B. Streptomycin | 2. Inhibits initiation of translation and causes misreading |
C. Tetracycline | 3. Inhibits binding of tRNA to ribosome |
D. Erythromycin | 4. Inhibit translocation of ribosomes along mRNA. |
- (a)
A B C D 4 1 2 3 - (b)
A B C D 3 4 1 2 - (c)
A B C D 1 2 3 4 - (d)
A B C D 2 3 4 1
Match List I with List II and select the correct answer using the codes given below the lists:
List I | List II |
A. Theory of mutation. | 1. Beadle and Tatum |
B. Theory of evolution | 2. Jacob and Monod |
C. One gene-one enzyme hypothesis | 3. Darwin |
D. Operation concept | 4. De Vries |
- (a)
A B C D 3 4 1 2 - (b)
A B C D 4 3 1 2 - (c)
A B C D 4 3 2 1 - (d)
A B C D 3 4 2 1
Consider the following statements:
1. Muton is a unit of gene mutation.
2. Recon participates in recombination.
3. Cistron is functional unit of DNA / Gene.
which of the statements given above are correct?
- (a)
Only 1
- (b)
Only 2
- (c)
1 and 2
- (d)
All of these
Consider the following statements:
1. The sugar present in DNA is deoxyribose
2. Circular DNA occurs in bacteria, mitochondria, and chloroplast.
3. The bond present between two strands of DNA is a hydrogen bond.
which of the statements given above are correct?
- (a)
1 and 2
- (b)
2 and 3
- (c)
1,2 and 3
- (d)
None of these
Consider the following statements:
1. Human beings have 23 pairs of chromosomes.
2. Sex chromosome in the human male is named XY.
3. Chromosomes are best seen in metaphase.
which of the statements given above are false about chromosomes?
- (a)
1 and 2
- (b)
2 and 3
- (c)
1,2 and 3
- (d)
None of these.
Consider the following statements about Progeria:
1. Progeria is the genetic disease associated with fast aging.
2. Progeria patients never live beyond the early twenties.
3. It happens due to point mutation replacing cytosine by thymine.
which of the statements given above are correct?
- (a)
1,2,3
- (b)
Only 1
- (c)
2 and 3
- (d)
2 and 3
A normal woman whose father was colorblind is married to a normal man, The sons would be
- (a)
75% Colorblind
- (b)
50% Colorblind
- (c)
All normal
- (d)
All colorblind
The absence of Y-chromosome in human beings causes
- (a)
Turner's syndrome
- (b)
Klinefelter's syndrome
- (c)
Down's syndrome
- (d)
No abnormality
Chromosomes be counted best in
- (a)
Metaphase
- (b)
Early prophase
- (c)
Mid prophase
- (d)
Late prophase
Which one of the following genetic disease is sex-linked?
- (a)
Royal haemophilia
- (b)
Tay-Sachs disease
- (c)
Cystic fibrosis
- (d)
Hypertension
Formation of RNA (mRNA) over DNA template is called
- (a)
translation
- (b)
transcription
- (c)
reverse transcription
- (d)
initiation
Match List I with List II and select the correct answer using the codes given below the lists:
List I | List II |
A. Discovery of transduction and conjugation | 1. Khurana |
B. Establishing the sex-linked inheritance | 2. Korenberg |
C. Isolation of DNA polymerase from E.coli | 3. Lederberg |
D. Establishing the complete genetic code | 4. Morgan |
- (a)
A B C D 4 3 2 1 - (b)
A B C D 3 4 1 2 - (c)
A B C D 4 3 1 2 - (d)
A B C D 3 4 2 1
Sexual reproduction causes genetic variation because of
- (a)
blending of genes
- (b)
chromosomal changes
- (c)
shuffling of genes
- (d)
all of the above
Which one among the following is not correct about Down's syndrome?
- (a)
It is a genetic disorder
- (b)
Affected individual has early aging
- (c)
Affected person has mental retardation
- (d)
Affected person has furrowed tongue
In the context of the genetic disorder, consider the following:
A woman suffers from color blindness, while her husband does not suffer from it. They have a son and a daughter. In this context, which one of the following statement is most probably correct?
- (a)
Both children suffer from color blindness
- (b)
Daughter suffers from color blindness while son does not suffer from it.
- (c)
Both children do not suffer from color blindness.
- (d)
Son suffers from color blindness while Daughter does not suffer from it.
Consider the following statements:
1. Genomics is the study of the sequencing the genomes of organisms.
2. Genomics includes intensive efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping efforts.
3. Genomics was established by Fren Sanger when he first sequenced the complete genomes of a virus and a mitochondrion.
which of the statements given above are correct?
- (a)
1 and 2
- (b)
2 and 3
- (c)
1 and 3
- (d)
1,2 and 3
In human beings, 45 chromosomes / single X / XO abnormality causes
- (a)
Down's syndrome
- (b)
Klinefelter's syndrome
- (c)
Turner's syndrome
- (d)
Edward's syndrome
A diseased man marries a normal woman and they get three daughters and five sons. All the daughters were diseased and sons were normal. the gene of this disease is
- (a)
sex-linked dominant
- (b)
sex-linked recessive
- (c)
sex-limited character
- (d)
autosomal dominant
A man and a woman, who do not show any apparent signs of a certain inherited disease, have seven children ( two daughters and five sons ). Three of the sons suffer from the given disease but none of the daughters are affected. which of the following mode of inheritance do you suggest for this disease?
- (a)
Autosomal dominant
- (b)
Sex-linked Dominant
- (c)
Sex-limited recessive
- (d)
Sex-linked recessive